Chronic kidney disease and hypertension clinical hypertension and vascular diseases 2015 edition kindle edition. Hypertension is both an important cause and consequence of chronic kidney disease evidence from numerous clinical trials has demonstrated the benefit of blood pressure control however it remains unclear whether available results could be extrapolated to patients with chronic kidney diseases . Vascular disease includes large vessel disease such as bilateral the most common cause of death in people with ckd is cardiovascular disease rather than kidney failure chronic kidney disease results in and other forms of cardiovascular diseases chronic kidney disease was the cause of 956000 deaths globally in 2013 up from . Hypertension is the major preventable cause of cardiovascular and chronic kidney diseases cardiovascular disease is the commonest cause of death and disability in the world therefore prevention or better treatment of hypertension would have a huge impact on global health. The purpose of this study is to determine if patiromer treatment in chronic kidney disease ckd subjects receiving spironolactone for the treatment of resistant hypertension will result in more persistent use of spironolactone through prevention of hyperkalemia and lead to improved blood pressure control compared with treatment with spironolactone alone placebo
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