Introduction liver cancer is the second leading cause of death worldwide accounting for 745000 deaths in 2012 1 and the fifth cause of cancer related deaths in japan 2 according to the japanese national vital statistics a total of 40099 persons 19208 men and 20891 women died of liver cancer in 2014 2 also data from the population based cancer registries in japan indicate that . Chronic liver disease and asian americans pacific islanders among asian americans chronic liver disease is a leading cause of death while the cause is not always known some cases can be initiated by conditions such as chronic alcoholism obesity and exposure to hepatitis b and c viruses. Patients transplanted for non cholestatic liver diseases report a significantly lower qol after lt in comparison to those with a cholestatic liver disease patients with viral hepatitis tend to suffer more from anxiety after lt than patients with alcoholic liver disease however others challenge these data101421. Chronic liver disease cld and cirrhosis are major sources of morbidity and mortality in the united states little is known about the epidemiology of these two diseases in ethnic minority populations in the united states. Declining liver cancer mortality rates among young adults ages 35 49 years may signal a future decline in overall us liver cancer mortality rates this was the case in japan where liver cancer mortality peaked a generation earlier than in the united states among the japanese birth cohort born during 1925 1939 35 36
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