Complications of chronic liver disease these complica tions are also markers for decompensated liver disease and most patients are given a diagnosis of cirrhosis in the presence of these complications decompen sated or unstable liver disease occurs in 2 to 10 of. Complications of chronic liver disease are secondary conditions symptoms or other disorders that are caused by chronic liver disease in many cases the distinction between symptoms of chronic liver disease and complications of chronic liver disease is unclear or arbitrary. Topics addressed ranged from liver disease during pregnancy the management of portal hypertension drug hepatotoxicity liver disease and ethnicity practical management of chronic hepatitis c and b and complementary and alternative therapies for liver disease to a state of the art lecture on hereditary hemochromatosis. Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis chronic liver disease refers to disease of the liver which lasts over a period of six months. Portal hypertension once it develops is the source of potentially devastating complications that include life threatening hemorrhage infection renal failure and coma parenchymal disease can result in coagulopathy as well as altered handling of both endogenous hormones metabolites and exogenous drugs substances
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