With an understanding of the basic mechanisms underlying these conditions practitioners will develop more effective strategies for recognition diagnosis and treatment written by four internationally renowned authorities on nms neuroleptic malignant syndrome and related conditions is the most comprehensive resource on the subject in existence. This second edition of neuroleptic malignant syndrome and related conditions answers the overwhelming need for a thorough up to date reference on nms it provides psychiatrists and mental health professionals primary care providers neurologists and other clinicians who deal with psychopharmacologic agents with a current balanced and . Neuroleptic malignant syndrome nms is a life threatening reaction that can occur in response to neuroleptic or antipsychotic medication symptoms include high fever confusion rigid muscles variable blood pressure sweating and fast heart rate complications may include rhabdomyolysis high blood potassium kidney failure or seizures. Neuroleptic malignant syndrome nms is a life threatening idiosyncratic reaction to antipsychotic drugs characterized by fever altered mental status muscle rigidity and autonomic dysfunction it has been associated with virtually all neuroleptics including newer atypical antipsychotics as well . Diagnosis and treatment of neuroleptic malignant syndrome nms are controversial because this potentially life threatening syndrome is rare and its presentation varies these factors make it difficult to evaluate treatments in controlled clinical trials and data about the relative efficacy of specific interventions are scarce
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