In commenting on the nimh matrics consensus statement on negative symptoms i do so as a clinical psychologist who has been involved in the investigation of psychological and psychosocial factors in schizophrenia and in the design and evaluation of psychological and psychosocial treatments for over 3 decades. Positive and negative symptoms syndromes in schizophrenia reliability and validity of different diagnostic systems volume 25 issue 1 v peralta m j cuesta j de leon. Positive and negative syndromes were studied in relation to demographic historical genealogical clinical psychometric extrapyramidal and follow up measures of 101 chronic schizophrenic patients. The positive and negative syndrome scale panss is a medical scale used for measuring symptom severity of patients with schizophreniait was published in 1987 by stanley kay lewis opler and abraham fiszbein it is widely used in the study of antipsychotic therapy the scale is known as the golden standard that all assessments of antipsychotic behavioral disorders should follow. The negative positive dichotomy of schizophrenic symptoms and syndromes is the current version of ongoing attempts to subdivide the multifarious clinical manifestations of schizophrenia into more simple homogeneous classes the theoretical background for the negative positive distinction in anglo saxon literature is not explicitly formulated although it rests on a hidden conceptual framework
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