chung sheng lin uric acid biology functions and diseases carlos g musso matilde navarro manuel vilas uric acid urea and creatinine implications for patients with diabetic vascular disease hairong nan 506 a biochemistry research trends series 856 4 0. chung sheng lin uric acid biology functions and diseases carlos g musso matilde navarro and manuel vilas uric acid urea and creatinine implications for patients with diabetic vascular disease hairong nan series title biochemistry research trends series responsibility santiago e castillo and ernesto w maldonado editors. Hyperuricemiauric acid metabolismso far as is known today uric acid serves no biochemical function in the body other than being an end product of purine metabolism. Uric acid generated from the metabolism of purines has proven and emerging roles in human disease serum uric acid is determined by production and the net balance of reabsorption or secretion by the kidney and intestine. Uric acid is the product of purine metabolism it is known that hyperuricemia defined as high levels of blood uric acid is the major etiological factor of gout a number of epidemiological reports have increasingly linked hyperuricemia with cardiovascular and neurological diseases studies
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